? ?????????????????? ????? ????? ???????


?????????????????? ?????

??????????? ???????? ???????? ??????? ??? ??? ????????? ??????? ??? ?????? ??? ??? ?????. ???? ?????????? ??????, ??? ?????? ?? ????????? ????? ??? ??????? ?? 24 ??? 48 ???? ??? ??? ?????? ???????? ??? ???????????, ?? ??? ???? ?? ???? ??????? ????? ?????. ????????, ??? ???? ?????????, ? ????? ?????? ?? ?????????? ?????? ???????? (??????? ??? ?????, ?????????????, ????? ??? ?????, ??????????? ??????? / ???????).

? ????? ??? ??????????? ???????????? ????? ? Neisseria meningitidis (?????????????????), ??? ?????????? ???? ???? ?????????, ????????? ??? ???? ????? ??? ????? ??? ??? ???????? ??? ??? ??? ???????? ??? ??????????. ? ???????? ???????? ?? ???? ???? ????????? ??? ?? ???????? ??????????? ?????? ??? ????? ?? ????? ???? ???? ??? ????????????? ???? (??????????: ?????, ?????????, ??????, ????) ???? ?? ??? ????? ?? ????????????? ????????? ??? ????? (????? ?????: ???????, ???????, ??????, ????????????? ?.??.).

? ???????????? ??? ???????????? ?????? ??????????? ?? ?????? ?????? ??? ???? ???? ??? ?? ????????????????, ????? ?? ?????????? ?????????? ?? ???? ?? ????? (?????????????? ??????). ?? ??????? ??????? ???????????? ?? ?????????? ?????? ??? ???????? ?????? ??????? (ClausHetalJInfectDis. 2005). ? ?????? ??????????? ?? ???????? ??????????? ? ???????? ?????????? ??????, ???? ?? ????????? ? ?????????? ?????? ??? ?? ??????????

???????? ????? ??????? ????????? ??? N. meningitidis: A, B, C, W135 ? Y??? ??? ????? ????? ?????????, ?? B ??? C ????? ?????? ????????? ??? ??? ?????????????????? ???? ???? ??????, ??? ?? ?, C, ? ???? ?.?.?. ??? A ???? ?????? ??? ??? ????? ????? W135 ????????? ???? ??????, ??? ????????? ????????? ??????????? ?? ????, ?????? ??? ?.?.?. ??????, ????????? ??? ? ?????????? ???????? ??? ????????? ??????? ?? ??? ?????? ??? ??????, ??????????? ??? ????????????? ??? ??????????????????? ????? ?????? ??????????

??????? ??? ???????????

?? ?????? ??? ?? ?????? ???????? (15-24 ????) ????????? ????? ????????? ??????? ??? ? ???????? ???? ?????? ???? ????? ????? (Tzanakaki G, National meningococcal reference laboratory, 2010, Report Athens), ??????? ??? ???? ???????? ??????:

o???????????? ?? ????, clubs ??? ?????? ?????? ??????????

o???????? ?? ?????? ??? ????? ?????? ?????, ????????? ???? ??? ?????????????? ? ??????????? ??????????

o???????????? ????????????? ? ?????? ???????? (?.?. ????????)

o????? ?????, ??????? ??????????????? (????)

o??????? ?? ???????? ?????? ????????

(Brigham 2009, Zuschneld 2008) 

????????, ?????? ?????? ??? ?????? ???????? ??? ?????????????? ???? ??? ??????? ???????? ????????????? ??????? (Sakou et al, Eur J Pediatr,2011), ???? ??? ?? ????????? ??????????? ???? ??? ??????? ?????? ? ?????? ????????? ???? ??? ?????? ??????????, ?? ?????????? ?? ??????? ??? ??????????? ?? ????? ?????????? ?????? ??? ??????? ?? ????????????? (Sakouetal.Vaccine.2009).

???????: ? ?????? ?????? ??? ????????? ???????

? ??????? ???????? ???????? ????? ???? ??? ????? ?? ????? ???????? ???????????? ??? ??????????? ??? ?????? ??? ???? ??? ??? ?????? ???. ?????? ????????? ??? ??????? ??? ?? ?????????? ??? ???????? ???? ??? ??? ??????. ????????, ?? ??????????? ?????????? ???? ?????? ???? ????? ?????????????? ? ??? ????????? ????????? ??? ????????? ??? ??? ??????? ???? ???????? ????? ??? ????????????? ?????? ???? ? ?????????? ????? ??? ??? ???????????? ????????????? ? ?????? ????????. ??????????? ?????? ?? ?????? ?????? ?? ?????? ?????? ???????? ???? ? ?????????? ?????, ? ?????????? ???????, ? ?????????? ???????? ????? ? ?.??.. ??? ????? ?????? ??? ? ????????? Rousseau ??????????? ??? ??????? ??? ??? ??????? ???????: ????????? ??? ?????: ? ??? ?????? ???? ???? ??????, ? ???? ???? ???? ?? ???. 

??? ????? ???? ???????? ??????? ??????? ???????? ??? ?????? ?????? ??? ?????? ???????? ??? ??? ???????? ??? ?? ?????????????? ??? ?????? ??? ??? ???????? ????? ??? ???????????? ????????. ??????, ?? ??????????? ?????????????? ??? ?? ?????????????? ?????????????? ??? ?????? ??????????? ????????? ???? ???????? ???????? ??? ?????? ???????? ??? ??? ??????????? ????????????. ?????????????? ??? ???? ??????????? ? ???????? ??? ???????? ????????? ??? ??????? ??????????? ???? ??????? ?????, ????? ?? ???? ????? ?????????? ? ????????? ????????? ?????. ??? ??????????, ?? ?????? ??? ??????????????? ?????? ??? ????????? ??? ??????? ???? ??? ??????, ????????? ???? ??? ???????????? ??? ???????? ??? ????????? ?? ???? ?????? ??????? (??????????????????? ??? ???????? ?????). ????????, ??? ?????????? ??? ????????? ?????? ??? ???? ??????? ??? ??????????? ???????, ??????? ?????????????? ?? ????????. ?? ???????????? ?????????? ????????? ?? ???????? ???????????? ???? ????? ??? ????????? ??? ???????? ?????? ??? ??????? ??????? ??? ??? ??????????????, ????????? ??? ????? ????????.

?????????? ??? ???????? ?????????????? ????? ? ????????? ???????????? ?????? ??? ??????? ??????, ?????? ??????? ?? ???????? ??????? (Sakou et al, Eur J Pediatr,2011).

??????? ???????????? ???? ??????? 

??????? ????????? ??? ??????? ??? ?????????? ??? ????? ??? ???????? ????????? ???? ??? ??? ??????, (Buttler 2006, Kassianos 2010, Walther 2011) ??????????? ?? ????????:

  • ???????? ??? ?????? ???????? ?? ????????? ??????????:
    • ??? ?????????? ???????? ??? ???????? ??? ?????????? ??? ?????, ???? ??? ??????? ????????????
    • ??????????? ????? ???????? ??? ????? ??? ?????????? ??????? ??? ??????
    • ????????? ??? ???????? ??? ??? 24-48 ???? ???? ??? ?????? ??? ?????????
    • ????? ?????? ?? ??????? ??? ??????????? ?????????
    • ???????? ?????????? ??? 2 ?????? ?? ??? ?? ????? ??? ????? ?? ????? ????? ?? ??? ??????? (??????, ???????, ?????? ??? ???????)

(??????????? ?, ????????? ? ??? ??????????. ??????????? ?????????, ??????????? 1999)

  • ?????????? ??????? ???? ??? ???????????: 
  • ????? ????? ??? ? ???????? ??????? ???????? ????? ? ?????????? ??????? ???? ??? ???????????
  • ???? ?????? ??????? ?? 2001 ?? ??????? ?????? ??? ????????????????? ?????? C
  • ????????? ??? ?? ??????? ????????????? ??????? ???? ??????? ??? ????? ????????????? ??? ??? ????? ??? ?? ?????? ??? ????? ??????????? ?? ?????? ??? ????? ????????????? ?????????? (Sakouetal.Vaccine.2009, Sakou et al, Eur J Pediatr,2011), ???? ??? ??? ?????????? ??????????? ??? ?????? ??? ?????????????????? ????:
  • ????? ????????? ?????????? ??? ????????? ? ??????????? ??? ?????? ?? ?? ?????????? ??????????? ??????? ???? ??? ?????????????????

  • ?? ??????? ????? ??????? ??? ?????????????? (???????? ?????? ???????? ???????????)
  • ??? ???????? ??????? ????????????
  • ????????? ????????? ??? ????????????????? ??? ????????? (A, C, W-135, Y)
  • ?????????? ??? ?????????? ??? ?? ?????? ????????? ??????????? ??? ??? ?????? ??? 11 ???? ??? ??? ?????????? ??? ???? ????????? ??????????? ???? ??????? ??????

????????? ??? ??????? ???????? ?????? (?.?.?.)

??????? ?? ???????? ?????? ??? ??????? ???????? ?????? (?.?.?.) ??? ?? ???????????? ???????? ??? ????????????? ??????, ?????????? ?????? ???. & ???. ???????? ???? ?? ???? 2012, ?? ??????? ???????? ??? ???????, ?? ??????? ??? ?????? ??? ?? ???? ??? ????????????, ?? ????? ???????? ?? ????????? ?????????? ??? ??? ?????? ??? ???????? ???? ?????????? ????????????? (??????? ?????????? ??? 50% ???????? ????? ?????? ??? ?? ???????? ??????  6? ???????? ????????? ???????? ????????, posterpresentation). ???????, ???????? ????????? ??????? ??? ?????????? ???? ??? ??????????? ?????????? ?????? ??? ?????????????, ???? ?? ??????? ???????????? ??? ??????? ??? ???????? ???, ??????????-????????????? ????????? ??????????? (????????? ??? ?? ??????????? ?? ??????? ???????????? ???? ??? ??????). ???? ?? ???????? ??? ?? ?????? ?? ?????? ??? ?.?.?., ???????????????? ??? ?????????? ?????????? ??? ?????? ??? ???? ???????? ??? ?.?.?. ??????? ?? ?? ???????? ??????. ?? ?????? ??????????? ????????? ?????????? ??? ?????????, ??? ?? ?????? ????????????? ??? ??????? ???? ????????? ????????????. ?? ???????? ??? ???????? ??? ??????? ????????? ?????????? ??????? ??? ??????? ??? ?? ????. ?????????? ?????? ??? ?????????? ?? ????? ????????? ??????????? ??? ?? ???????? ??? ????????? ???? ??????? ????????????.

????????????

1.ClausHetal. J Infect Dis. 2005; 191:1263-1271.

2.Sakou II, Tsitsika AK, Papaevangelou V, Tzavela EC, Greydanus DE, Tsolia MN. Vaccination coverage among adolescents and risk factors associated with incomplete immunization. Eur J Pediatr 2011;Vol 170,Issue 11,pg 1419-1426.

3.TzanakakiG, Nationalmeningococcalreferencelaboratory, 2010, ReportAthens

4.Brigham KS et al, Curr Opin Pediatr.2009;21:437-443

5.Zuschneld I, et al. Euro Surveill. 2008;13:pll=19031

6.???????? ?. ? ???????? ??? ?????? ??? ???????: ? ?????? ??? ????????? ??? ??? ???????????, ???????? ???????? ??????????, 2011, ????? 1, ???????? 2, ???.33-38.

7.Sakou II, Tzanakaki G, Tsolia MN, Sioumala M, Barbouni A, Kyprianou M, Papaevangelou V, Tsitsika A, Blackwell CC, Kafetzis D, Kremastinou J. Investigation of serum bactericidal activity in childhood and adolescence 3-6 years after vaccination with a single dose of serogroup C meningococcal conjugate vaccine.Vaccine. 2009 Jul 16;27(33):4408-11. Epub 2009 Jun 3.

8.Butler KM. Meningococcal meningitis prevention programs for college students: a review of the literature. Worldviews Evid Based Nurs.2006;3(4):185-93.

9.Kassianos G. Vaccination for tomorrow: the need to improve immunisation rates. J Fam Helath Care.2010;20(1):13-6.

10.Walther S. A parents decision on immunization: making the right choice. Pediatrics, May 2011.

11.??????????? ?, ????????? ? ??? ??????????. ??????????? ????????? ??? ???????????, ????? 1, ???????? ???????? ?????? 1999, ???. 208-209.

12.????? ?, ??????????????? ?, ????????????? ?, ????? ?, ???????? ?. ??????? ??????? ?????? ??? ?? ???????????, ?? ????? ???????? ?? ????????? ?????????? ??? ??? ???????? ??? ???????? ???????????. ??? ???????? ??? 6?? ????????? ?????????? ???????? ????????, ??-25.

13.???????????? ?. ????????? ??? ?? ??????????? ?? ??????? ???????????? ???? ??? ?????? ??? ?? ??????? ... ?????? ???, ?????? ?????, 2000.

??????? ?. ????????


Έγγραφα

i-miniggitidokokkiki-nosos-stous-efibous.doc


09-06-2014