? ?????????????????? ????? ????? ???????
?????????????????? ?????
? ??????????? ???????? ???????? ??????? ??? ??? ????????? ??????? ??? ?????? ??? ??? ?????. ???? ?????????? ??????, ??? ?????? ?? ????????? ????? ??? ??????? ?? 24 ??? 48 ???? ??? ??? ?????? ???????? ??? ???????????, ?? ??? ???? ?? ???? ??????? ????? ?????. ????????, ??? ???? ?????????, ? ????? ?????? ?? ?????????? ?????? ???????? (??????? ??? ?????, ?????????????, ????? ??? ?????, ??????????? ??????? / ???????).
? ????? ??? ??????????? ???????????? ????? ? Neisseria meningitidis (?????????????????), ??? ?????????? ???? ???? ?????????, ????????? ??? ???? ????? ??? ????? ??? ??? ???????? ??? ??? ??? ???????? ??? ??????????. ? ???????? ???????? ?? ???? ???? ????????? ??? ?? ???????? ??????????? ?????? ??? ????? ?? ????? ???? ???? ??? ????????????? ???? (??????????: ?????, ?????????, ??????, ????) ???? ?? ??? ????? ?? ????????????? ????????? ??? ????? (????? ?????: ???????, ???????, ??????, ????????????? ?.??.).
? ???????????? ??? ???????????? ?????? ??????????? ?? ?????? ?????? ??? ???? ???? ??? ?? ????????????????, ????? ?? ?????????? ?????????? ?? ???? ?? ????? (?????????????? ??????). ?? ??????? ??????? ???????????? ?? ?????????? ?????? ??? ???????? ?????? ??????? (ClausHetal. JInfectDis. 2005). ? ?????? ??????????? ?? ???????? ??????????? ? ???????? ?????????? ??????, ???? ?? ????????? ? ?????????? ?????? ??? ?? ??????????.
???????? ????? ??????? ????????? ??? N. meningitidis: A, B, C, W135 ? Y. ??? ??? ????? ????? ?????????, ?? B ??? C ????? ?????? ????????? ??? ??? ?????????????????? ???? ???? ??????, ??? ?? ?, C, ? ???? ?.?.?. ??? A ???? ?????? ??? ??? ????. ? ????? W135 ????????? ???? ??????, ??? ????????? ????????? ??????????? ?? ????, ?????? ??? ?.?.?. ??????, ????????? ??? ? ?????????? ???????? ??? ????????? ??????? ?? ??? ?????? ??? ??????, ??????????? ??? ????????????? ??? ??????????????????? ????? ?????? ??????????.
??????? ??? ???????????
?? ?????? ??? ?? ?????? ???????? (15-24 ????) ????????? ????? ????????? ??????? ??? ? ???????? ???? ?????? ???? ????? ????? (Tzanakaki G, National meningococcal reference laboratory, 2010, Report Athens), ??????? ??? ???? ???????? ??????:
o???????????? ?? ????, clubs ??? ?????? ?????? ??????????
o???????? ?? ?????? ??? ????? ?????? ?????, ????????? ???? ??? ?????????????? ? ??????????? ??????????
o???????????? ????????????? ? ?????? ???????? (?.?. ????????)
o????? ?????, ??????? ??????????????? (????)
o??????? ?? ???????? ?????? ????????
(Brigham 2009, Zuschneld 2008)
????????, ?????? ?????? ??? ?????? ???????? ??? ?????????????? ???? ??? ??????? ???????? ????????????? ??????? (Sakou et al, Eur J Pediatr,2011), ???? ??? ?? ????????? ??????????? ???? ??? ??????? ?????? ? ?????? ????????? ???? ??? ?????? ??????????, ?? ?????????? ?? ??????? ??? ??????????? ?? ????? ?????????? ?????? ??? ??????? ?? ????????????? (Sakouetal.Vaccine.2009).
???????: ? ?????? ?????? ??? ????????? ???????
? ??????? ???????? ???????? ????? ???? ??? ????? ?? ????? ???????? ???????????? ??? ??????????? ??? ?????? ??? ???? ??? ??? ?????? ???. ?????? ????????? ??? ??????? ??? ?? ?????????? ??? ???????? ???? ??? ??? ??????. ????????, ?? ??????????? ?????????? ???? ?????? ???? ????? ?????????????? ? ??? ????????? ????????? ??? ????????? ??? ??? ??????? ???? ???????? ????? ??? ????????????? ?????? ???? ? ?????????? ????? ??? ??? ???????????? ????????????? ? ?????? ????????. ??????????? ?????? ?? ?????? ?????? ?? ?????? ?????? ???????? ???? ? ?????????? ?????, ? ?????????? ???????, ? ?????????? ???????? ????? ? ?.??.. ??? ????? ?????? ??? ? ????????? Rousseau ??????????? ??? ??????? ??? ??? ??????? ???????: ????????? ??? ?????: ? ??? ?????? ???? ???? ??????, ? ???? ???? ???? ?? ???.
??? ????? ???? ???????? ??????? ??????? ???????? ??? ?????? ?????? ??? ?????? ???????? ??? ??? ???????? ??? ?? ?????????????? ??? ?????? ??? ??? ???????? ????? ??? ???????????? ????????. ??????, ?? ??????????? ?????????????? ??? ?? ?????????????? ?????????????? ??? ?????? ??????????? ????????? ???? ???????? ???????? ??? ?????? ???????? ??? ??? ??????????? ????????????. ?????????????? ??? ???? ??????????? ? ???????? ??? ???????? ????????? ??? ??????? ??????????? ???? ??????? ?????, ????? ?? ???? ????? ?????????? ? ????????? ????????? ?????. ??? ??????????, ?? ?????? ??? ??????????????? ?????? ??? ????????? ??? ??????? ???? ??? ??????, ????????? ???? ??? ???????????? ??? ???????? ??? ????????? ?? ???? ?????? ??????? (??????????????????? ??? ???????? ?????). ????????, ??? ?????????? ??? ????????? ?????? ??? ???? ??????? ??? ??????????? ???????, ??????? ?????????????? ?? ????????. ?? ???????????? ?????????? ????????? ?? ???????? ???????????? ???? ????? ??? ????????? ??? ???????? ?????? ??? ??????? ??????? ??? ??? ??????????????, ????????? ??? ????? ????????.
?????????? ??? ???????? ?????????????? ????? ? ????????? ???????????? ?????? ??? ??????? ??????, ?????? ??????? ?? ???????? ??????? (Sakou et al, Eur J Pediatr,2011).
??????? ???????????? ???? ???????
??????? ????????? ??? ??????? ??? ?????????? ??? ????? ??? ???????? ????????? ???? ??? ??? ??????, (Buttler 2006, Kassianos 2010, Walther 2011) ??????????? ?? ????????:
(??????????? ?, ????????? ? ??? ??????????. ??????????? ?????????, ??????????? 1999)
|
????????? ??? ??????? ???????? ?????? (?.?.?.)
??????? ?? ???????? ?????? ??? ??????? ???????? ?????? (?.?.?.) ??? ?? ???????????? ???????? ??? ????????????? ??????, ?????????? ?????? ???. & ???. ???????? ???? ?? ???? 2012, ?? ??????? ???????? ??? ???????, ?? ??????? ??? ?????? ??? ?? ???? ??? ????????????, ?? ????? ???????? ?? ????????? ?????????? ??? ??? ?????? ??? ???????? ???? ?????????? ????????????? (??????? ?????????? ??? 50% ???????? ????? ?????? ??? ?? ???????? ?????? 6? ???????? ????????? ???????? ????????, posterpresentation). ???????, ???????? ????????? ??????? ??? ?????????? ???? ??? ??????????? ?????????? ?????? ??? ?????????????, ???? ?? ??????? ???????????? ??? ??????? ??? ???????? ???, ??????????-????????????? ????????? ??????????? (????????? ??? ?? ??????????? ?? ??????? ???????????? ???? ??? ??????). ???? ?? ???????? ??? ?? ?????? ?? ?????? ??? ?.?.?., ???????????????? ??? ?????????? ?????????? ??? ?????? ??? ???? ???????? ??? ?.?.?. ??????? ?? ?? ???????? ??????. ?? ?????? ??????????? ????????? ?????????? ??? ?????????, ??? ?? ?????? ????????????? ??? ??????? ???? ????????? ????????????. ?? ???????? ??? ???????? ??? ??????? ????????? ?????????? ??????? ??? ??????? ??? ?? ????. ?????????? ?????? ??? ?????????? ?? ????? ????????? ??????????? ??? ?? ???????? ??? ????????? ???? ??????? ????????????.
????????????
1.ClausHetal. J Infect Dis. 2005; 191:1263-1271.
2.Sakou II, Tsitsika AK, Papaevangelou V, Tzavela EC, Greydanus DE, Tsolia MN. Vaccination coverage among adolescents and risk factors associated with incomplete immunization. Eur J Pediatr 2011;Vol 170,Issue 11,pg 1419-1426.
3.TzanakakiG, Nationalmeningococcalreferencelaboratory, 2010, ReportAthens
4.Brigham KS et al, Curr Opin Pediatr.2009;21:437-443
5.Zuschneld I, et al. Euro Surveill. 2008;13:pll=19031
6.???????? ?. ? ???????? ??? ?????? ??? ???????: ? ?????? ??? ????????? ??? ??? ???????????, ???????? ???????? ??????????, 2011, ????? 1, ???????? 2, ???.33-38.
7.Sakou II, Tzanakaki G, Tsolia MN, Sioumala M, Barbouni A, Kyprianou M, Papaevangelou V, Tsitsika A, Blackwell CC, Kafetzis D, Kremastinou J. Investigation of serum bactericidal activity in childhood and adolescence 3-6 years after vaccination with a single dose of serogroup C meningococcal conjugate vaccine.Vaccine. 2009 Jul 16;27(33):4408-11. Epub 2009 Jun 3.
8.Butler KM. Meningococcal meningitis prevention programs for college students: a review of the literature. Worldviews Evid Based Nurs.2006;3(4):185-93.
9.Kassianos G. Vaccination for tomorrow: the need to improve immunisation rates. J Fam Helath Care.2010;20(1):13-6.
10.Walther S. A parents decision on immunization: making the right choice. Pediatrics, May 2011.
11.??????????? ?, ????????? ? ??? ??????????. ??????????? ????????? ??? ???????????, ????? 1, ???????? ???????? ?????? 1999, ???. 208-209.
12.????? ?, ??????????????? ?, ????????????? ?, ????? ?, ???????? ?. ??????? ??????? ?????? ??? ?? ???????????, ?? ????? ???????? ?? ????????? ?????????? ??? ??? ???????? ??? ???????? ???????????. ??? ???????? ??? 6?? ????????? ?????????? ???????? ????????, ??-25.
13.???????????? ?. ????????? ??? ?? ??????????? ?? ??????? ???????????? ???? ??? ?????? ??? ?? ??????? ... ?????? ???, ?????? ?????, 2000.
??????? ?. ????????
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